Department of Biotechnology, College of Science, University of Baghdad, Baghdad, Iraq
Research
Serum level evaluation of CRP, IL- 22 and IL-35 in women with polycystic ovary syndrome
Author(s): Sarah Itemad Abdul Sahib* and Jinan M. J. Al-Saffar
Background: Polycystic Ovarian Syndrome (PCOS) is the most well-known endocrine condition among women, with 18- 27% prevalence. PCOS is a pro-inflammatory state, certain cytokines are correlated with women who have PCOS.
Objective: The study aims to estimate the impact of some inflammatory mediators like CRP and interleukin 22 (IL-22) and interleukin 35 (IL-35) on PCOS.
Methods: Eighty women, ranging in age from nineteen to forty, were part of the study; thirty of these women had polycystic ovarian syndrome, and thirty of these women had delayed childbearing. The other twenty women were healthy. We analyzed the CRP, IL-35, and IL-22 levels, after separating the serum by the ELISA method.
Results: The results showed a decrease in CRP, IL-22 and IL-35 in patients with PCOS and in delayed ch.. Read More»