Department of Medical Application of Laser, National Institute of Laser Enhanced Sciences, Cairo University, and Giza, Egypt
Research
Can we use Anti Mullerian hormone in follicular fluid as a potential biomarker for oocyte and embryo quality during an In-vitro Fertilisation cycle ?
Author(s): Rabab M. Sorour*, Osama Fekry, Tamer Taha, Sondos Salem and Mohamed A. ElNoury
Background: Anti-Müllarian Hormone (AMH) is a member of the transforming growth factor-β superfamily. It is a yield of granulosa cells lining the FSH dependent growing preantral and small antral follicles. Some authors suggested a relationship between the serum AMH level and oocyte and embryo quality during ovarian stimulation through an IVF cycle.
Material and methods: This prospective observational clinical study was done at Ain Shams University, maternity hospital (IVF Unit), and a private ICSI center from May 2019 to June 2020. Our study used the ALU- QPCR technique and ELISA (Immunotech Beckman Coulter, Marseille, France). To accurately measure the cell-free DNA (cfDNA) level and FF AMH levels respectively, in 35 follicular fluid samples from 15 patients undergoing ICSI.
Results: Our results displaye.. Read More»