Department of Pharmaceutical Chemistry, College of Pharmacy, Al-Zhraa University for Women, Karbala, Iraq

Publications

• Research   
  Synthesis, characterization, and evaluation of transition metal complexes of 4-Amino-5-Phenyl-4H-1,2,4-Triazole 3-Thiol as anti-breast cancer
  Author(s): Israa A. Bachay* and Noor H. Naser
  
  Background: Breast cancer is a disease where cells in the breast grow out of control, forming lumps. If these lumps are not treated, they can spread to other parts of the body. The disease often starts in the milk ducts or lobules. Early forms, called 'in situ', can be found and treated before they become life-threatening. Aim: evaluation the novel synthesize a series of 1,2,4-triazole-based metal complexes and evaluate their structural features and cytotoxic activity against breast cancer cells. Methodology: A multi-step synthetic route was employed starting from ethyl benzoate to obtain the triazole ligand (Compound III), which was subsequently complexed with various metal ions (Ni²?, Co²?, Cd²?, Cr³?, Zn²?) to afford complexes IVa–IVe. The compounds were characterized using FT-IR and ¹H NMR spectroscopy. Cytotoxicity was assessed in vitro.. Read More»
  

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