Department of Obstetrics and Gynecology, Faculty of Medicine, Tabuk University, Tabuk, Saudi Arabia
Research
Assessing warm saline's role in alleviating pain in office hysteroscopy: A systematic review and meta-analysis
Author(s): Salwa Neyazi, Khalid Akkour, Nada Alayed, Omar Alzaydan, Eman Al Shehri, Shadan Binsaeedan, Ahmed Sherif*, Alhassan Khedr, Sondos Al Hawamdeh, Mohammed Alatawi, Mohammad Atlam and Karim Abdelsalam
Background: This systematic review and meta-analysis evaluated the effectiveness of using warm saline as a distension medium compared to room temperature saline in reducing pain and improving patient satisfaction during office hysteroscopy. Methodology: Following PRISMA guidelines and registered in PROSPERO (CRD420251074073), we systematically searched MEDLINE, Scopus, Web of Science, and Cochrane Central for RCTs from inception to June 2025. Our search combined MeSH terms and keywords related to hysteroscopy, distension media, and pain management. We included RCTs that compared warm and room temperature saline in women undergoing diagnostic or operative office hysteroscopy. Two authors independently extracted data and assessed the risk of bias using the Cochrane Risk of Bias tool. Continuous outcomes were pooled as mean differences (MD) and dichotomous outcomes as odds ratios (OR) wi.. Read More»