Department of Pharmacy, College of Pharmacy, Uruk University, Baghdad, Iraq
Research
Prevention of hypotention after spinal anesthesia in cesarean section ? A prospective randomized comparative clinical study on ephedrine vs. norepinephrine
Author(s): Sami R. Hasan, Afraa Ibrahim, Talib Razq M and Hayder A. Fawzi*
Background: Ephedrine (EP) and Norepinephrine (NE) considered an option to maintain maternal blood pressure during Spinal Anesthesia (SA) since hypotension is considered a common consequence of SA. The aim of the current study is the assessment of the maternal and neonatal safety and efficacy of NE compared to ephedrine in treatment of SA induced hypotension in cesarian delivery.
Methods: A prospective, randomized comparative clinical study, that involved 100 participants, they were divided into two groups: Group N: received NE (10 μg/ml). Group E: received EP (5 mg/ml). The research was conducted at tertiary Teaching Hospital, and it lasted from February 2021 until October 2022.
Results: Overall, the incidence of hypotension was significantly lower in NE group, and when assessed at various time periods (for.. Read More»