Nashwa N. El-Khazragy
Departments of obstetrics and Clinical Pathology/Hematology, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Publications
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Research
Evaluation of Serum level of thrombomodulin in cases with preeclampsia
Author(s): Hayam F. Mohammed*, Yasser M. Abou Taleb, Nashwa N. El-Khazragy, Sohaila K. Ahmed and Rehab M.Abdelrahman
Background: Preeclampsia is a multisystmic disorder of unknown cause. Endothelial cell damage has recently been suggested to underlie the pathologic change in preeclamptic pregnancy. Thrombomodulin an endothelial cell surface glycoprotein act as a co-factor for thrombin catalyzed activation of protein C. activated protein C inhibits coagulation by inactivation the coagulation factor Va and VIIIa. Aim of the Work: to assess the changes in thrombomodulin level in women with preeclampsia. Patients and Methods: This prospective case-control study was conducted on 123 women at Ain Shams University Maternity Hospital. Results: Regarding clinic-pathological features of pre-eclampsia patients and healthy control groups, our study found that there was high significant difference (p≤0.01) between hypertensive and no.. Read More»