Department of Anesthesia and Reanimation, Faculty of Medicine, Selçuk University, Konya, Turkey
Research Article
Investigation of routine tranexamic acid application in gynecological oncology
Author(s): Belma Gozde Ozdemir*, Feyza Duran, Leyla Aghakishiyeva, Betul Dik, Burcu Gezer Yurteri, Emine Aslanlar, Ahmet Bilgi and Cetin Celik
Background/Aim: Tranexamic acid is a drug that controls bleeding by affecting fibrinolytic pathways. This study investigated the effect of routine use of Tranexamic Acid (TXA) on blood loss in gynecologic oncology surgeries.
Materials and methods: 160 gynecologic oncology patients who underwent surgery at the Department of Obstetrics and Gynecology at Selçuk University between 2023 and 2024 were evaluated. Patients were divided into two groups: those who received TXA (n=80) and those who did not (n=80). TXA was administered intravenously at a dose of 1 gram intraoperatively.
Results: A significant reduction in drain fluid volume was observed in the TXA group. While the postoperative decrease in hemoglobin levels was substantial in both groups, the TXA group had more stable values. Although blood loss decreas.. Read More»