Department of Pharmaceutical Chemistry, College of Pharmacy, University of Kufa, Kufa, Iraq

Publications

• Research   
  Genetic insights into type 2 diabetes mellitus: Evaluating the role of TLR4 (Asp299Gly) polymorphism in an Iraqi women
  Author(s): Ahmed J. Mohammed*, Akeel Abo Alard and Balsam G. Hassan
  
  Background: Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder with significant genetic contributions, including Toll-Like Receptor 4 (TLR4) gene polymorphisms such as Asp299Gly, which may influence disease susceptibility and progression. Objective: This study aims to evaluate the association of TLR4 (Asp299Gly) gene polymorphism with T2DM and its impact on clinical parameters in an Iraqi women. Methods: A case-control study was conducted with 200 female participants (100 women with Type 2 Diabetes Mellitus (T2DM) and 100 healthy controls) aged 35–60 years. Clinical and biochemical parameters, including fasting plasma glucose (FPG), HbA1c, insulin levels, HOMA IR, QUICKI and lipid profiles, were measured. Genotyping for TLR4 (Asp299Gly) gene polymorphism was performed using PCR and restriction en.. Read More»
  

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