Abstract
Author(s): Rabab Awad Farhood ,Vian Hussam Almansi Alqani , Ashwaq Kadhim Mohammed
Background: The purpose of this study was to look at how DHEA affects ovarian reserve parameters in patients with low ovarian reserve. At the end of the experiment, a significant number of women were able to become pregnant. We also noticed differences in blood hormone levels between pregnant and non-pregnant women. Aim of the study: The purpose of this study was to see how DHEA affected ovarian reserve indices in those who had low reserves. Patients and methods: In the department of obesteric and gynecology at Adiwaniyah Maternity and Pediatirc teaching Hospital, From februrary 2023 to october 2023, in this study 30 infertile women with poor ovarian reserve were enrolled they were treated using DHEA and followed up for 6 months by evaluating pregnancy outcome and changes in serum hormonal levels including FSH, LH, estradiol, testosterone, AMH and DHEA. Results: In this study, five patients (16.7 %) succeeded in achieving pregnancy. The mean age of pregnant women was lower than that of non-pregnant women, 27.20 ±1.92 years versus 31.12 ±4.64 years, respectively, but the difference in mean age did not reach statistical significance (p = 0.057). There was no significant difference in mean body mass index between pregnant and non-pregnant women, 23.90 ±1.28 kg/m2 versus 25.01 ±1.91 kg/m2, respectively (p = 0.090). There was also no significant difference in duration of infertility between pregnant and non-pregnant women, 3.00 ±0.71 years versus 3.72 ±1.28 years, respectively (p = 0.251). Conclusion: The results of this study revealed that treatment with DHEA can improve ovarian reserve markers and pregnancy outcome in women with poor ovarian reserve.