Author(s): BEATA NAWORSKA1, AGNIESZKA SARWIÅSKA2, MARIOLA CZAJKOWSKA3
Introduction. Tumours of the female reproductive organs are diagnosed in women of all ages,but the highest incidence is reported in women between 40 and 70 years of age. Anovulatorycycles, hormonal fluctuations, and the ageing process of the immune system are the prevailingrisk determinants of neoplastic diseases of the female genital tract in perimenopausal women.Study objective.To analyse the prevalence of cancer of the female reproductive system indifferent age groups, with a focus on perimenopausal women. Materials and methods. A questionnaire survey was conducted among 198 women hospitalisedat surgical and conservative gynaecology departments of the 2nd Specialist Hospital in Bytom,Poland.Results. Ovarian cancer was the most common gynaecological cancer in the study group. In 81patients tested for CA-125, 71 – 150 U/ml levels were detected in 38%, 36-70 U/ml in 15%, and151-300 U/ml in 6% of these patients; significantly elevated Ca 125 levels (over 300 U/ml) werefound in 16% of these women.Conclusions: Ovarian cancer was the most common gynaecological cancer in the study group.It was statistically significantly more prevalent in women who reached menopause between theage of 45 and 50 years.