gynecology and obstetrics medical project, gynecology journal, obstetrics, gynecologic oncology, reproductive medicine, gynecological endoscopy, ultrasonography, gynecology articles

Ginekologia i Poloznictwo
ISSN 1896-3315 e-ISSN 1898-0759

The significance of tricuspid regurgitation detected in first trimester screening for the follow-up of the pregnancies



Introduction. The presence or absence of tricuspid regurgitation (called also tricuspid insuf-ficiency) can be used to calculate the specific risk for chromosomal defects occurrence. It hasbeen shown that tricuspid regurgitation is independent of the concentration of free ß-hCG andPAPP-A risk factor for trisomy of 21, 13 and 18 pairs of chromosomes.Aim of the study. Analysis of the fate of fetuses with tricuspid regurgitation diagnosed duringultrasound at 11 to 13 + 6 weeks of gestation. Material and methods. 788 pregnant women were examined at an average age of 36.9 years(range 20-48 years), of whom 748 women were in the single pregnancies and 40 women inmultiple pregnancies. To further analyzes only the pregnant in single pregnancies were inc-luded. The study was conducted with use of Logiq 7 ultrasound machine, transabdominal probe3,5mHz and vaginal probe 7MHz. In any case beyond the nuchal translucency measurementand tricuspid valve flow, the presence or absence of the nasal bone, the flow in the venousduct and the anatomy of the fetus were assessed.Results. Tricuspid regurgitation was found in 22 fetuses (2.8%). Increased risk of aneuploidybased on ultrasound and ß-hCG and PAPP-A determination was found in 17 (77.3%) women.The most common chromosomal defect in examined material was trisomy 21, it accounted forthree-quarters of all cases. Ultrasound examination carried out in the first and second trime-ster (16-20 weeks of pregnancy) revealed a heart defect in 10 fetuses (45.4%).Conclusions. Tricuspid regurgitation was rarely diagnosed and was associated with an abnor-mal nuchal translucency values ??and was the first symptom of heart defects in the fetus. Isolatedtricuspid regurgitation was accompanied by the correct karyotype. The most common geneticsyndrome coexisting with tricuspid regurgitation was trisomy 21.