gynecology and obstetrics medical project, gynecology journal, obstetrics, gynecologic oncology, reproductive medicine, gynecological endoscopy, ultrasonography, gynecology articles

Ginekologia i Poloznictwo
ISSN 1896-3315 e-ISSN 1898-0759

Hemorrhagic complications in a patient with von Willebrand disease


Author(s): Edyta Barnaś (DE), Joanna Skręt-Magierło (AE), Jolanta Starzak-Gwóźdź (DE), Gabriela Żuk (E), Martyna Świerk (E), Anna Piotrowska (B), Sylwia Nicpoń (D), Maciej Czerwiński (F), Bogdan Mac (F), Andrzej Skręt (ADE)

Von Willebrand disease (vWD) is one of the most common congenital bleeding disorders. Its prevalence in the general population is estimated at approximately 0.3–1.3%. Depending on the type, it is inherited as an autosomal dominant trait, or more rarely as a recessive disease. It is caused by deficiency or dysfunction of von Willebrand factor (vWF). The disease usually presents with spontaneous bleeding from mucous membranes and soft tissues. Increased bleeding occurs during surgical or dental procedures, and abundant menstrual periods are additionally present in women. During pregnancy, the level of von Willebrand factor normalizes and symptoms tend to become less severe. However, the risk of hemorrhage increases in the postpartum period due to a rapid decline in vWF level, hence this period requires special attention. The aim of the study is to present a case of a young woman diagnosed with von Willebrand disease, who had bleeding after cesarean section in early puerperium and after endometrial cyst removal 5 years later.