Author(s): Mohammed Hussain Mostafa, Hussam M. Samir*, Marwa S. Sayed
Aim: In women with repeated IVF-failure, pregnancy rate was compared between sequential embryo transfer (ET: ET on day 3 and 5) vs. day 3 ET. Patients and Methods: A randomized controlled clinical trial was conducted from September 2019 till September 2020 on 80 women with repeated IVF-failure: sequential ET (n=40) vs. day 3 ET (n=40). Pregnancy outcomes were compared between the two groups. Results: Sequential ET, compared with day 3 ET, showed higher chemical, clinical, and ongoing pregnancy, i.e., with sequential ET showing 37%, 35%, and 32.5%, respectively; and with day 3 ET showing 17.5%, 15%, and 12.5%, respectively. Conclusion: For patients with repeated IVF-failures, sequential ET improved the chemical, clinical, and ongoing pregnancy rates as long as good quality embryos were available.