Author(s): STEFAN SAJDAK1,3, AGATA PALUCH1, MA?GORZATA KAMPIONI1,2,KATARZYNA WÓJCICKA1
The antiphospholipid syndrome (APS) is a multisystem autoimmune disease connected withvascular thrombosis and pregnancy complications with elevated antiphospholipid antibody titers.Pregnant women with this syndrome require intensive monitoring with the use of biophysicaltesting of the fetus and doppler ultrasonography. The aim of the therapy is to reduce or eli-minate the risk of thromboembolism and in effect to decrease the frequency of complicationsduring pregnancy as well as limit antibody production. Pregnancy lost occurrence may exceed90% in untreated APS patients. Treatment indications including aspirin and heparin can reducethe risk to 25%. Medications applied in treating complications during pregnancy in womenwith APS are: aspirin, heparins and less often corticosteroids and immunoglobulines. Patientsresistant to the above are advised to undergo plasmapheresis.